Imaging in Pregnancy

This SIG has recently changed its name to include imaging modalities beyond fetal ultrasound, which is still the mainstay of prenatal imaging diagnosis. Activities focus predominantly on pre-congress courses, but the SIG also wishes to produce tools for clinical aid (systematic reviews, management algorithms) and to offer a forum for ongoing engagement between SIG members, and with other professionals involved in Prenatal Diagnosis, including those working in the laboratory and clinical settings.

SIG Mission Statement

To improve the knowledge and use of both established and innovative imaging techniques in prenatal diagnosis, and to increase the awareness of fetal imaging specialists (Maternal-fetal medicine specialists, radiologists and radiographers) in fetal dysmorphology.

SIG Topics of Discussion/Interest

  • Prenatal Dysmorphology of Genetic Syndromes
  • Detection of Congenital Anomalies
  • Ultrasound Markers of Aneuploidy
  • The Genetic Sonogram
  • Prenatal and postmortem MRI
  • Color and pulsed Doppler
  • New Ultrasound Technologies
  • First trimester screening
  • ltrasound-guided invasive diagnostic procedures

Prenatal Imaging Following Zika Exposure

With a clear link to microcephaly established, international health care agencies now recommend serial ultrasounds for women with positive Zika testing.

World Health Organization
Centers for Disease Control and Prevention (CDC)
Pan American Health Organization (PAHO)
European Centre for Disease Prevention and Control (ECDC)
Public Health England

Detailed imaging guidelines are available from the International Society of Ultrasound in Obstetrics and Gynecology and highlight a balance of measurements, specific intracranial findings, detection of other abnormalities and local resources including the availability of ultrasound imaging. Amniocentesis for Zika viral detection is considered with extrapolation from other viral teratogens such as cytomegalovirus infections.

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Ultrasound changes, often in the CNS, can appear later in pregnancy after initial early images without concern. Ultrasound remains the modality for imaging surveillance. For some affected fetuses, head circumference is maintained, but CNS damage is evident supporting the need for detailed intracranial evaluations in addition measurements. A new study from Brazil utilizing ultrasound and subsequent CT/MRI offers further delineation of the pattern of CNS changes including enlarged ventricles, abnormalities of the corpus callosum, brainstem abnormalities and calcification in the transition zone between the white and gray matter. The latter appears to be unique to Zika.

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As with all aspects of Zika infection, from absolute risk, confounders of risk, testing methods to treatment, the discrete imaging patterns are emerging as the pandemic evolves. First trimester exposure is likely to result in the greatest risk; although potential damage especially to the CNS can occur following exposure at all trimesters. Hydrops, genital hypoplasia, multiple pteygium, placental signs of inflammation (thickening, calcifications) and growth restriction have all been noted.

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Long-term studies will be essential to evaluate the outcomes of exposed infants. For all infants with Zika exposure, it is critical to gain knowledge about this emerging infectious teratogen. International efforts is needed and we encourage you to participate.

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SIG Leadership

Co-Chair: Cheryl Albuquerque, MD, MBA

Co-Chair:  Luc De Catte, MD, PhD

Board Liaison: Monique Haak, MD, PhD

Meeting Minutes

12 July 2016 - Berlin, Germany
11 July 2016 - SIGs and Education Committee
13 July 2015 - Washington, DC USA
23 July 2014 - Brisbane, Australia
05 June 2013 - Lisbon, Portugal
06 June 2012 - Miami, Florida, USA
14 July 2010 - Amsterdam, Netherlands
04 June 2008 - Vancouver, Canada